Five people were injured Saturday after a two-vehicle crash on U.S. Highway 59 south of Lawrence, the Douglas County Sheriff’s Office said.

Sheriff’s office spokesman George Diepenbrock said via email that the crash took place around 4:45 p.m. Saturday at the intersection of North 1100 Road and U.S. 59, which is about 1.5 miles south of Lawrence. According to preliminary information, Diepenbrock said, a vehicle was going west on North 1100 Road, failed to stop at a stop sign and was struck by a southbound vehicle on U.S. 59.

Three people in the westbound vehicle were injured, two of them seriously, Diepenbrock said. Two people in the southbound vehicle were also seriously injured. All five injured people were taken to area hospitals.

Diepenbrock said deputies shut down the southbound lanes of the highway so that medics could get the patients out and so that the crash scene could be investigated. The highway’s lanes reopened before 7 p.m., he said.