Serologicals Corp., a supplier of antibodies to drug developers, said on Wednesday it swung to a fourth-quarter loss as hefty charges dragged down results.

The company reported a loss of $11.7 million, or 34 cents per share, reversing year-earlier profit of $3.5 million, or 12 cents per share.

The latest quarter includes one-time charges of $39.4 million, including $38 million in impairment and exiting costs and $1.4 million for inventory write-offs after the company decided to abandon plans for opening its $35 million plant in Lawrence’s East Hills Business Park. The company also plans to cease production operations in Toronto by mid-2006.

Revenue rose 26 percent to $87.1 million from $69.2 million.

Annual 2005 earnings slid to $2.7 million, or 8 cents per share, from $17.7 million, or 59 cents per share, in 2004. Revenue increased to $274.9 million from $195.9 million.

Shares of Serologicals gained 25 cents to close Wednesday at $23.13, then climbed another $1.23 in after-hours trading.