KANSAS CITY — Adalberto Mondesi hit a 464-foot three-run homer, Salvador Pérez added his 18th home run this season, and the Kansas City Royals beat the Boston Red Sox 5-3 on Friday night for only their second win in their last 13 games.

Kansas City trailed 1-0 before Mondesi’s third-inning home run off Nick Pivetta (6-3), Mondesi’s fourth home run in nine games this season. Mondesi has nine RBIs.

Before a season-high crowd of 29,870 at Kauffman Stadium, Kris Bubic (2-2) won despite allowing two runs and five hits in 2 2/3 innings. Greg Holland pitched a perfect ninth for his fourth save, and the Royals stopped their six-game losing streak.

Boston’s Christian Arroyo was ejected by plate umpire Jim Wolf after he took a called third strike for the second out of the ninth on a pitch that Arroyo thought was inside.

Whit Merrifield had his fourth straight multi-hit game, including an RBI double in the fifth that boosted Kansas City’s lead to 4-2.

The Red Sox went 2 for 9 with runners in scoring position and stranded eight runners.

Boston faced Kansas City for the first time since dealing outfielder Andrew Benintendi to the Royals on Feb. 10 as part of a three-team trade. Benintendi is missing the series because of a broken rib.

Kansas City used an opener for the first time this season, and Kyle Zimmer allowed three hits in two scoreless innings.

Pivetta gave up three runs and six hits in five innings. He is 0-3 in four starts after starting the season 6-0.

Alex Verdugo’s RBI single put Boston ahead in the third, and J.D. Martinez hit a run-scoring single in the fifth that closed the Red Sox to 3-2.

Pérez homered in the seventh off Matt Andriese, a drive just over the wall in right.

Rafael Devers hit his 17th homer, a solo drive in the eighth off Scott Barlow, who had not allowed a home run in 38 innings.