Kansas City, Mo. ? After striking out his first three times, Lorenzo Cain came through in the ninth inning for the Kansas City Royals.

Cain hit a tying, two-run homer off Jose Valverde with two outs in the ninth and Eric Hosmer had a winning RBI single in the 10th, helping the Royals rally for a 3-2 victory over the Detroit Tigers on Wednesday.

Cain struck out three times against Detroit ace Justin Verlander, who pitched seven scoreless innings.

“It was a crazy game from having the hat trick to being able to get a ball out of here was huge,” Cain said. “I was glad I was able to get a good pitch and get it over the fence for us to tie the game up.”

Drew Smyly pitched a one-hit eighth, then allowed a leadoff single in the ninth to Hosmer and was replaced by Valverde. He retired Santiago Perez on a flyout and struck out Billy Butler as Hosmer stole second — becoming the first Kansas City runner in scoring position.

Cain fouled off three pitches, then sent an 85 mph offering over the wall in left-center. Valverde blew a save for the third time in 12 chances.

Cain was not sure it was going to clear the fence.

“I put it on the barrel, but after that it was either wind or carry,” Cain said. “I thought it was in the gap. I was just blowing for it to go out for me and it did.”

Verlander did not allow a batter past first base, giving up three singles, striking out eight and walking two in a 117-pitch outing, his second-highest total this season.

“It was a tough outing, Verlander being Verlander as usual, dominating,” Cain said. “I say continue to battle, got a pitch up, put a nice easy swing on it and it got over the fence.”

Verlander has a 15-2 record with a 2.56 ERA in 25 starts against the Royals.

“It hurts,” Verlander said. “You’ve got two outs and two strikes, and when the ball leaves the yard, it’s not a good feeling. It only tied the game, so we immediately need to change our mindset to OK, let’s win it. To lose it that way, it’s a tough pill to swallow.

“Losing period stinks. When you lose one that’s so close to a win makes it that much more difficult.”

Greg Holland (2-1) pitched a perfect 10th, striking out Torii Hunter and Miguel Cabrera and retiring Prince Fielder on a lineout, and Miguel Tejada singled off Phil Coke (0-4) leading off the bottom half.

Tejada advanced to third on Alcides Escobar’s sacrifice and Alex Gordon’s groundout to first, and Hosmer singled to center.

“That was a great win,” Hosmer said. “We’re down to our last strike with the closer on the mound. That’s just the character of this team. We’re not going to give up until the last out is made.

“Cain had a day like he did, the first couple of at-bats, strikes out. The way he comes up in the last inning with two strikes, it’s battling right there.”

Tigers manager Jim Leyland’s post-game press conference was brief, lasting 97 seconds.

“Verlander showed why he’s the horse today,” Leyland said. “He was terrific, absolutely terrific.”