Columbia, Mo. ? The last time Oklahoma State played at Missouri in October 2008, the Cowboys came away with a big upset of a school that appeared poised to be No. 1.

The Cowboys (6-0, 3-0 Big 12) are the big dogs this time around, sixth-ranked and favored by a touchdown to keep their unbeaten season rolling and end Missouri’s 10-game home winning streak. They’re road tested after scoring 38 points at Texas — most in school history — last week.

“I remember watching them on TV and it’s just like, ‘Dang, they’re a pretty good offense,'” Missouri defensive end Brad Madison said.

Missouri (3-3, 1-2) beat Iowa State by 35 points last week at home, getting a bit of a breather in a schedule that’s only getting tougher. Coming off a four-year stretch that produced 40 victories, the Tigers have yet to win in consecutive weeks and have losses on the road to another pair of unbeatens, Oklahoma and Kansas State.

They’re about to get their third shot, beginning a four-game stretch against schools ranked most of the season.