Waco, Tex. ? Robert Griffin ran for a season-high 107 yards, Terrance Ganaway rushed for a career-high 200 yards and three scores and No. 25 Baylor beat Iowa State, 49-26, on Saturday.

Tevin Elliott returned a fumble 86 yards for a touchdown for the Bears (4-1, 1-1 Big 12), who bounced back from a 36-35 loss last weekend to No. 20 Kansas State.

Two key booth reviews also aided the Bears, who ran for 391 yards and won their fourth in a row at home.

Darius Reynolds had 178 yards receiving and two touchdowns, and Steele Jantz threw for three scores as Iowa State (3-2, 0-2) lost its second straight after a 3-0 start.

Ganaway’s 3-yard TD run gave Baylor a 28-14 advantage in the third, but the Cyclones were deep in Bears territory after Jantz connected with Darius Reynolds on a 57-yard pass.

Jantz was running to his left when Gary Mason Jr. stripped the Iowa State quarterback. Elliott scooped up the loose ball and ran into the end zone untouched to give Baylor a 35-14 lead with 6:18 left in the third.

After a review of the play, it was ruled the ball popped out just before Jantz’s knee hit the ground.

It was second key booth review that went in Baylor’s favor.

In the second quarter, it was ruled on the field that Griffin lost a fumble. However, the play was overturned when replay officials said Griffin’s arm was in motion before he dropped the ball.

Griffin threw a 15-yard touchdown pass to Kendall Wright on the next play to tie the game at 14. Even though Griffin hit on his first 11 passes to start the game, Baylor didn’t score in the opening quarter because it lost two fumbles. Griffin’s first incompletion came with 28 seconds remaining in the first quarter when he threw the ball away while scrambling away from pressure.

Baylor’s first touchdown came on Griffin’s 1-yard sneak. The Heisman trophy contender then dodged the near fumble and threw the TD pass to Wright.

Iowa State sacked Griffin three times and constantly hounded Baylor’s star.

Behind Ganaway, the Bears turned to its ground game to power their offense.

The Bears took a 21-14 advantage on a 58-yard drive, all of which came on running plays. Ganaway, who lost a fumble in the first quarter, had a 13-yard carry to set up Glasco Martin’s 1-yard plunge into the end zone.

Ganaway also had TD runs of 2 and 22 yards in the fourth quarter.

Iowa State’s James White rushed for 148 yards, including a 76-yard TD in the third. Jantz and Reynolds hooked up three times for 76 yards on Iowa State’s opening drive. Reynolds caught a 10-yard TD pass to put the Cyclones on top 7-0.

Jantz also threw a 1-yard touchdown pass to Reid Branderhorst in the second quarter.