Archive for Monday, September 20, 2010

Drug developed by KU researchers could help diabetics

September 20, 2010, 8:22 a.m. Updated September 21, 2010, 4:39 p.m.


A drug developed at Kansas University has the potential to stop a debilitating diabetes condition after successful trials in mice.

Rick Dobrowsky, professor of pharmacology and toxicology, and Brian Blagg, professor of medicinal chemistry, found that the new drug can stop and occasionally reverse the condition — known as diabetic peripheral neuropathy, or DPN — in mice.

DPN can cause pain in the extremities, and is the second-leading cause of amputations, after injuries.

The researchers said that of the approximately 24 million diabetics in the United States, about 60 percent of them suffer from DPN at some point.

The drug, KU-32, also showed it could restore sensory neuron function to damaged nerve tissue, a characteristic that neither of the current FDA-approved drugs to treat DPN have shown.


number3of5 7 years, 6 months ago

Any news as to when this might be on the market. I know several people who could benefit from this drug.

dontsheep 7 years, 6 months ago

Diabetes is cured by a change in diet, increased hydration and exercise. Drugs just mask the symptoms.

whats_going_on 7 years, 6 months ago depends on what type of diabetes. Some very elderly people can't exercise, so that isn't going to help.

dontsheep 7 years, 6 months ago

Elderly people can exercise. Sure, they may not be able to run 3 miles...but there is plenty they can do.

The best cure for diabetes is to prevent it from happening in the first place.

joe_cool 7 years, 6 months ago

I'll assume you are talking about Type II diabetics. No real prevention methods for Type I.

I'll be waiting for this drug to come out. Hopefully, it comes out before I need it.

rolliepollie 7 years, 6 months ago

So people who have to inject insulin several times a day are just "masking" their symptoms? If they just change their diet, hydrate more, and exercise, their pancreas' will automatically start producing insulin.

Type-1 Diabetics over the world--put down your needles and pick up a bottle of water. You are cured says dontsheep!

dontsheep 7 years, 6 months ago

Improving the alkalinity of our diet, hydrating and exercise balances the body. The reason people suffer from diabetes is because they are out of balance.

The NIH is funding 20 people who otherwise could not afford treatment to attend a 21 day program run by Dr. Robert Young.

ConcernedCynic 7 years, 6 months ago

Wow, this is one of the most uninformed statements I ever read. There is not just one type of diabetes or even just one type of "type 2" diabetes (more like thousands of types of type 2 diabetes). Thus, there is not one "cure" for diabetes. While I agree that lifestyle plays a significant role in many types of type 2 diabetes, some people who are active their entire life and eat a heathy diet will still develop diabetes.

Larry Miller 7 years, 6 months ago

dontsheep: I've not seen any scientific studies on that "cure."

dontsheep 7 years, 6 months ago

You have to look for them. Most don't because that means they have to take responsibility for their own health.

Why would any pharmaceutical company fund a study that would eliminate the need for their products? You do know that's who funds the studies these days right? It's been happening since about 1904.

Do some research on the Rockefeller Foundation.

dontsheep 7 years, 6 months ago

How about the NIH in 2001?

As I said above, they are now funding 20 people to go thru a 21 day diet and lifestyle course to see if their symptoms go away. Wanna bet?

BTW...It's nearly impossible to find "academic" studies not controlled by large corporations and phamra companies now-a-days.

Did you research the Rockefeller Foundation? Happens all around us. Even the American Cancer Society only spends 15% of their $1B annually on research.

yourworstnightmare 7 years, 6 months ago

Good idea, shardwurm. That, or raise taxes. It ain't free, buck-o.

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