Denver ? Safety Ryan Clark got his wish: replacement Tyrone Carter took one to the house, and Clark got to fly home with his teammates this time.

Carter started in place of Clark as a precaution Monday night and made the big play that sparked the Steelers to their fifth straight victory, taking the first of his two interceptions 48 yards for a touchdown in Pittsburgh’s 28-10 win over the Denver Broncos.

Clark nearly died following a game in Denver two years ago because of a rare blood disorder that is aggravated by playing in high altitude, so Steelers coach Mike Tomlin decided to hold him out of the game.

He said he didn’t want to risk Clark’s health or burden his teammates and family members with worry.

“Ryan likes to play. He’s probably hacked off at me that I didn’t play him,” Tomlin said. “But he will get over it.”

He already is, apparently.

“My goal for this trip was to go back with the team on the plane,” Clark said. “Last time I came out, I didn’t make it back with them.”

Clark was hospitalized in Denver in October 2007 when complications from sickle-cell trait prevented oxygen from flowing into his spleen. He later needed operations to remove his spleen and gall bladder, and he lost more than 30 pounds before he finally began feeling better more than two months later.

He missed the second half of that season, but recovered and resumed his career last season, when the Steelers won the Super Bowl.

Carter capped his night with his second interception with 15 seconds left, and Clark, dressed in charcoal sweats and a smile on the sideline, jumped up and down in celebration, then clicked the heels of his tennis shoes as he exited the field.

“I was excited for him,” Clark said. “It was a big win. He did an awesome job. His first interception really put us in the game.”

“I might be like Wally Pipp,” he added with a chuckle. “I’d better get back fast.”

Hines Ward caught two short touchdown passes from Ben Roethlisberger, including one in which he hauled in a pass in the flat and hurdled cornerback Champ Bailey on his way into the end zone, a final indignity for Denver that capped the scoring with 1:22 remaining and emptied the stadium.

Rashard Mendenhall rumbled over the Broncos for 155 yards on 22 carries as the Steelers (6-2) handed Denver its second straight loss after the Broncos opened the season 6-0 under rookie coach Josh McDaniels.

Carter’s first interception return gave Pittsburgh a 7-3 halftime lead even though the Steelers had generated just three first downs and were outgained 183-54 in the first half.

An ecstatic Clark was among the first players to swarm Carter, the first defender to pick off a Kyle Orton pass all season. His only interception before throwing three Monday night was a Hail Mary that Patriots wide receiver Randy Moss pulled down in a game last month.

“I’ll tell you, Ryan is like a brother to me. We’ve been in this thing together for a long time,” Carter said. “The bond is so tight between all of us.”