Madrid, Spain ? Andy Roddick lost to David Ferrer in five sets, giving Spain a commanding 2-0 lead Friday over the defending champion United States in their Davis Cup semifinal.

The fifth-ranked Ferrer defeated No. 8 Roddick, 7-6 (5), 2-6, 1-6, 6-4, 8-6, before a near-capacity crowd of 21,000 at the Las Ventas bullfighting arena.

Earlier, top-ranked Rafael Nadal gave the hosts the early advantage with a 6-7 (5), 6-4, 6-3, 6-4 win over Sam Querrey.