Kansas City, Kan. Turnovers proved costly to the Chargers.
SFT threw two interceptions and lost four fumbles.
Both teams failed to score in the first half, but Chargers quarterback Ryan Fike finally found the end zone in the third on a seven-yard run.
K.C. Piper also scored in the third, but the game remained tied 7-7 at the end of regulation.
Fike again scored for Santa Fe Trail in the first overtime, but the score was matched by Piper to force a second overtime.
The Pirates managed a field goal in the second extra stanza, and the Chargers failed to score.
Santa Fe Trail (0-1) will entertain Leavenworth Immaculata on Friday.
K.C. Piper 17, Santa Fe Trail 14 (2OT)
Santa Fe Trail007070- 14
K.C. Piper007073- 17
Santa Fe Trail Scoring
Ryan Fike 7 run (Chase McIver kick)
Fike 7 run (McIver kick)
Santa Fe Trail highlights - Fike 14 rushes, 30 yards, 2 TDs, 7-12 passing. Jake Kober four catches, 72 yards.