Afghanistan ? Regional officials said Wednesday that 51 villagers, some of them women and children, were killed in recent fighting in western Afghanistan. The U.S.-led coalition said it had no reports of civilian deaths.

The governor of southern Kandahar province also reported some civilians may have been killed during a clash there Tuesday night that left 13 dead, including two women.

Afghan President Hamid Karzai repeated his demands that more be done to prevent civilian casualties during military operations, saying he has been meeting regularly with officials of coalition and NATO forces trying to solve the problem.

“The intention is very good in these operations to fight terrorism. Sometimes mistakes have been made as well, but five years on, it is very difficult for us to continue to accept civilian casualties,” Karzai told reporters.

“We can no longer accept civilian casualties the way they occur,” he added. “It is not understandable anymore.”