Arlington, Texas ? Phil Hughes was working on a no-hitter in the seventh inning of his second major-league start when a hamstring injury cost him a chance to make history.

The Yankees’ prized prospect is expected to miss four to six weeks, a sour end to an otherwise encouraging night for the last-place club. New York responded to criticism from owner George Steinbrenner in a big way Tuesday with a 10-1 rout of the Texas Rangers.

Indians 12, Blue Jays 4

Cleveland – Rocked for three homers in the first inning, C.C. Sabathia buckled down to stay unbeaten, and Jhonny Peralta had a career-high five RBIs.

Athletics 5, Red Sox 4

Boston – Dan Johnson doubled home the winning run in the 10th inning after Jonathan Papelbon had his first blown save of the season, and Oakland stopped surging Boston.

Tigers 5, Orioles 4

Detroit – Pinch-hitter Sean Casey hit a tiebreaking single with one out in the eighth.

Twins 9, Devil Rays 1

St. Petersburg, Fla. – Sidney Ponson pitched seven impressive innings, and Michael Cuddyer drove in two for Minnesota before leaving with an injury.

Mariners 5, White Sox 2

Seattle – Richie Sexson hit a two-run home run, and Jarrod Washburn allowed four hits in seven innings to lead Seattle.