Mariners 2, Red Sox 1, 11 inn.

Seattle – Jose Lopez was watching unpredictable Manny Ramirez – just like many curious people do at Red Sox games.

As Boston Red Sox catcher Jason Varitek, left, walks off the field, Seattle Mariners players greet Ichiro Suzuki (51) after Suzuki scored the winning run. The Mariners beat the Red Sox, 2-1, in 11 innings Wednesday in Seattle.

Lopez noticed that Ramirez was positioned close to the left-field line in the bottom of the 11th, creating a large gap in left-center.

Lopez pulled Joel Pineiro’s pitch into the gap for a double, scoring Ichiro Suzuki and helping the surging Mariners beat Boston.

Suzuki drew a one-out walk off Pineiro (1-1), the former Mariners starter. Lopez then hit a 1-0 pitch that eluded a leaping, twisting Ramirez, the ball caroming past center fielder Coco Crisp and allowing Suzuki to score easily.

“I’m not going to make excuses. I hung a pitch,” Pineiro said, before adding the ankle he twisted stepping on teammate Eric Hinske’s heel during pregame stretching Monday still hurts.

Orioles 4, Yankees 0

Baltimore – Roger Clemens was denied his 350th victory by the Baltimore Orioles, who used a four-run sixth inning and an overpowering pitching performance by Erik Bedard to beat the Yankees.

White Sox 5, Devil Rays 3

St. Petersburg, Fla. – Mark Buehrle pitched seven strong innings as the White Sox came from behind to beat the Rays.

Athletics 13, Indians 7

Cleveland – Jack Cust had a career-high five RBIs, Shannon Stewart finished with four hits and the Oakland Athletics snapped a five-game losing streak.

Blue Jays 5, Twins 4

Minneapolis – Gregg Zaun hit a two-run homer and the Toronto Blue Jays overcame four errors to win for the fifth time in six games.