Lawrence police surrounded a Sixth Street hotel about 9:30 Thursday morning and took four individuals into custody.
Lawrence Police Department spokeswoman Kim Murphree said one individual, a Lawrence man, was arrested in connection with a Sunday morning robbery at Hy-Vee, 3504 Clinton Parkway.
According to a police report at the time, a grocery store cashier suffered minor injuries when a robber sprayed her in the face with a substance that may have been pepper spray.
Murphree said the department would be interviewing the individual.
Hotel manager Hansa Bhakta said she rented the room to an individual Wednesday night.