Chicago's Jim Thome launches a two-run home run against Kansas City. The White Sox defeated the Royals, 5-2, on Tuesday night in Chicago.

Chicago ? The names caught Jim Thome’s attention: Lou Gehrig and Fred McGriff.

Thome hit his 493rd homer, pulling into a tie with those two sluggers for 23rd on the career list, and Javier Vazquez won his third straight decision as the Chicago White Sox beat the Kansas City Royals, 5-2, on Tuesday night.

“Those are awesome names,” Thome said. “As you play as a young guy and you come up through the big leagues and you mention those types of names, it really kind of puts it in perspective.”

Danny Richar and Paul Konerko also homered for the White Sox, who won for the second time in 10 games and dropped Kansas City back into last place in the AL Central.

Vazquez (11-6) pitched six-plus inning, allowing two runs – one earned – and five hits. He struck out three, walked two and hit two batters.

Bobby Jenks pitched a perfect ninth for his 35th save in 40 chances, one night after the Royals’ Joey Gathright broke his string of 41 consecutive batters retired. Jenks had to settle for a share of the record with Jim Barr of the San Francisco Giants.

Thome’s RBI double to right off Royals starter Leo Nunez gave the White Sox a 1-0 lead in the first inning. After a double by Josh Fields in the third, Thome homered on a 1-1 pitch off Nunez, his 21st of the season and one closer to No. 500.

“People talk about it,” Thome said. “It’s tough because you can’t go and try and get home runs, I always said that. Home runs are unique things. There’s getting the right pitch, and you have to put the good part of the bat on it, and you might go two weeks and not hit one.”

Kansas City scored in the fourth on Emil Brown’s sacrifice fly, but Richar got it back on a two-out solo shot in the bottom of the inning. It was his third of the season and gave the White Sox a 4-1 lead.

“We’re a little tired,” said Royals manager Buddy Bell. “We tried to stay away from doing some things BP-wise and things like that to kind of give the guys a break.”

In his fifth major-league start, Nunez (2-1) gave up four runs and six hits in four innings. He struck out four and walked two.