New York Jets quarterback Chad Pennington and Buffalo Bills linebacker Takeo Spikes are out for the season after being injured in games Sunday.
A person with knowledge of Pennington's injury told the Associated Press on Monday that he had a torn rotator cuff - the same injury he suffered last year and had offseason surgery to repair. The person, who declined to be identified because the team had not made an official announcement, said an MRI exam revealed the injury.
Spikes, a leader of Buffalo's defense, will be sidelined because of a torn right Achilles' tendon.
Pennington was hurt in Sunday's 26-20 overtime loss to Jacksonville.
Backup Jay Fiedler also damaged his shoulder Sunday and will be sidelined, leaving third-stringer Brooks Bollinger to play quarterback against Baltimore this weekend.
Pennington and Spikes were among several NFL stars injured on Sunday, including Patriots safety Rodney Harrison, Eagles kicker David Akers and Bengals tackle Willie Anderson.
The Eagles replaced distractions with injuries. Akers probably will miss Philadelphia's game at Kansas City next week because of a torn hamstring, while Donovan McNabb's status is uncertain.
Akers, who collapsed to the ground in pain after the opening kickoff, fought through the injury to make a 23-yard field goal with nine seconds left in a 23-20 victory over Oakland on Sunday.
McNabb played with a sore chest, strained lower abdomen and a shin contusion. He finished with 365 yards passing and two touchdowns while throwing a career-high 52 passes.
Harrison's status was uncertain Monday after he injured his knee in a victory at Pittsburgh the previous day. Coach Bill Belichick refused to disclose any information until he is required to file an injury report with the league Wednesday.
Tackle Matt Light left Heinz Field on Sunday with a cast on his right leg, but Belichick didn't announce his status, either.
Anderson, Cincinnati's Pro Bowl tackle, is scheduled for an MRI on his strained back today.
Minnesota safety Willie Offord will miss the rest of the season because a knee injury.
Arizona QB Kurt Warner will miss next week's game against San Francisco in Mexico City because of a strained right groin.
Arizona (0-3) also lost right tackle Oliver Ross (hand) and defensive tackle Russell Davis (left biceps tendon), possibly for the season.
Dolphins coach Nick Saban said the teams was awaiting results of an MRI exam on linebacker Junior Seau's calf injury. Seau said Sunday he didn't think the injury was serious.