De Soto Ryan Schendel connected on touchdown passes of five yards to Austin Bloss and 16 yards to Ryan Kush as Wellsville handed De Soto its first loss of the season.
The Eagles (2-2) led, 7-0, at halftime and struck first in the third quarter. De Soto (3-1) cut the margin to 14-7 in the third period on a six-yard pass from Jake Morse to Austin DeGraeve.
Wellsville will play host to Prairie View on Friday, and De Soto will play host to Anderson County.
Wellsville 14, De Soto 7
Wellsville - 0 - 7 - 7 - 0 - - - 14
De Soto - 0 - 0 - 7 - 0 - - - 7
W - Austin Bloss 5 pass from Ryan Schendel (Schendel kick)
W - Ryan Kush 16 pass from Schendel (Schendel kick)
D - Austin DeGraeve 6 pass from Jake Morse (Neil Erisman kick)