President Bush and other Pacific Rim leaders ended their annual economic summit Saturday with an indirect challenge to European countries to help revive global free-trade negotiations by cutting their hefty farm subsidies.

The 21 members of the Asia-Pacific Economic Cooperation also addressed the threat of a possible bird flu pandemic, pledging to be open about disclosing outbreaks, boost surveillance and build a register of experts that can advise countries on combating the disease.

But it was the trade issue that dominated the two-day APEC summit, just three weeks before a key World Trade Organization meeting in Hong Kong.

The leaders, who clearly blamed Europe for the deadlock in remarks on the sidelines of the summit, stopped short of naming the continent in their statement on trade. Officials said it was too politically sensitive.