Massachusetts ? A Missouri radio talk show host was arrested on murder charges Monday for allegedly poisoning his wife by spiking her Gatorade with a chemical found in antifreeze.

Prosecutors said James Keown, 31, began poisoning his wife when the couple moved to Massachusetts in January 2004, after he lied to her about being accepted to Harvard Business School.

Keown was arrested at the radio station where he worked in Jefferson City, Mo. He later made a court appearance via video and said he would not fight efforts to return him to Massachusetts.

Middlesex Dist. Atty. Martha Coakley said the motive for the killing may have been financial. The couple was broke, and Julie Keown, 31, had a $250,000 life insurance policy. Her husband was never able to collect because the death came under investigation.