Louisville, Ky. ? Few games have gotten off to a wilder start than Louisville-Pittsburgh on Thursday night — two touchdowns in the first 25 seconds, both on kickoffs.

But by game’s end, the result was routine: another lopsided Louisville victory.

Michael Bush rushed for 115 yards and two touchdowns, and Art Carmody tied a school record with four field goals as No. 24 Louisville controlled the game in the second half en route to a 42-20 victory over the Panthers.

Louisville (6-2, 2-2 Big East) has won two straight after losing its first two league games and temporarily falling out of the Top 25. The Cardinals, wearing black jerseys for the first time since the 1984 season, became bowl-eligible with the victory in front of a record crowd of 42,692 fans at Papa John’s Cardinal Stadium.

“At the beginning, it kind of felt like it was a little video game,” Bush said. “After that, we got ourselves together, and we made a couple of nice plays, and we were able to get the win. Things just settled down in the second half.”

Pitt (4-5, 3-2) had a three-game winning streak snapped. The Panthers must win their final two games, against Connecticut and No. 18 West Virginia, if they are to extend their streak of consecutive bowl appearances to six.

Louisville, known for its high-scoring offense, wore the Panthers down with long, clock-chewing drives after halftime. The Cardinals scored the final 23 points and held a commanding edge in time of possession — 37:10 to 22:50 for Pittsburgh — and never punted.

Louisville running back Michael Bush breaks through a hole created by Deriontae Taylor (47) and Jason Spitz during the first half of a 42-20 victory over Pittsburgh. The Cardinals won Thursday in Louisville, Ky.

Bush’s second score, a three-yard run in the third quarter, was his 20th rushing touchdown of the season, tying the school record set by Lenny Lyles in 1957 and matched by Eric Shelton last season.

Bush, the NCAA Division I-A scoring leader, left the game after that with a sprained left foot. X-rays taken Thursday were negative, and Louisville spokesman Rocco Gasparro said Bush would undergo an MRI exam on Friday. Bush said he “felt fine” after the game.

Bush, who had 16 carries, also caught four passes for 59 yards.

Carmody kicked field goals of 46, 47, 32 and 36 yards, matching the school single-game record set by Nate Smith against Houston in 2000. The 46-yarder was a career-best, but Carmody booted a 47-yarder minutes later.

Entering the game, Carmody had attempted only eight field goals this season, making six.

“The deal was to try to force field goals and minimize the touchdowns and come up with a couple of turnovers,” Pittsburgh coach Dave Wannstedt said. “I felt like we had that going on defense. But in the second half, we’ve got to get a couple of scores.”

Louisville trailed in the final minute of the first half before Carmody’s 47-yarder, which put the Cards up 22-20 at the break.

“That was a big swing for us right there,” Louisville coach Bobby Petrino said.