Kansas City, Mo ? Lyndsey Medders made a game-winning three-pointer with 0.2 seconds remaining Tuesday, lifting No. 18 Iowa State to a 64-62 victory over Colorado in the first round of the Big 12 Conference tournament.

Katie Robinette added 22 points and 10 rebounds for the Cyclones (23-5 overall, 12-4 Big 12), who trailed 50-42 with 6:45 remaining.

The Cyclones will face No. 14 Texas Tech in the quarterfinals today.

The loss ended the coaching career at Colorado for Ceal Barry, who led the Buffaloes for 22 years. She announced her resignation last month and finished with a mark of 427-241.

For a while, it looked like she would coach at least one more day. Barry, who won 510 career games — including four seasons at Cincinnati — will take a spot in the Colorado athletic department.

Iowa State went on a 7-0 run to cut the deficit to 50-49 with 4:11 remaining, but Anna Nedovic’s three-pointer gave Colorado (8-19, 2-14) a four-point lead.

After the teams traded baskets, Mary Fox hit a three to bring Iowa State to 55-54. The Cyclones forced the Buffaloes into a shot-clock violation on the next possession, but Veronica Johns-Richardson stole the ball from Fox, giving possession back to Colorado.

Lisa Kriener and Johns-Richardson each made two free throws to push Colorado’s lead to 59-54.

Iowa State's Anne O'Neil, top, hugs teammate Mary Fox to celebrate their 64-62 victory over Colorado in the first round of the Big 12 Conference tournament. ISU advanced Tuesday in Kansas City, Mo.

Anne O’Neil made two free throws for the Cyclones with 16.4 seconds remaining, cutting the deficit to 62-61.

Colorado created a wide-open layup for Nedovic, but she missed it, and Robinette got the rebound with six-seconds left. She moved the ball up the floor to O’Neil, who passed it over to Medders for the winning shot.