DNA testing may lead to new mad cow source

? The government hopes DNA analysis can pinpoint the herd of the cow that tested positive for mad cow disease and lead investigators to the source of the animal’s brain-wasting illness, the Agriculture Department’s chief veterinarian said Saturday.

Genetic testing is needed because of mistakes in how the beef cow was labeled and how its tissues were stored, John Clifford told The Associated Press in an interview

The cow, a “downer” that could not walk, was delivered last November to a plant where animals unfit for human consumption are killed. The department has not identified the owner or the plant.

The cow’s type of breed was mislabeled, possibly because the animal had been soiled heavily with manure, and its tissues were mixed with tissues from other cows, Clifford said.

“When we went back to this particular owner, the breed we identified, he indicated he did not sell that breed. He sold another breed,” Clifford said. “In addition to that, we found that after the tissues were processed, there was some mixing.”

Parts from the diseased animal and four other cows were supposed to be kept in separate waste barrels, but some of the waste was combined, Clifford said.

Department officials think they have found the right herd. To confirm that, they must find relatives of the dead cow and test DNA.

“We’re pretty confident that we have the herd, but we want to make sure,” Clifford said. “Testing is being done now on tissue from cows that may have been herdmates.”

In this June 16 file photo, The U.S. top representative at the American Institute of Taiwan, Douglas Paal, samples U.S. beef in a guarantee that it is mad

Finding the herd will help track the cow’s feed and explain how the animal became infected. The mad cow disease is only known to spread through the feeding of infected cattle remains to other cattle. The U.S. has banned this practice since 1997.

When he announced the mad cow test results on Friday, Agriculture Secretary Mike Johanns pointed out that U.S. cattle “move all across the country.”

“They might be born in one state; they might be fed to a certain weight in another state,” said Johanns, a former governor of Nebraska, a major beef state. “They might be fed out in another state and slaughtered yet in a fourth state.”

The new case was confirmed by an internationally recognized laboratory in England. A series of tests in the U.S. had produced conflicting results.

U.S. officials had declared the cow to be free of the disease in November, but the department’s inspector general ordered a new round of tests that came back positive and led to the British tests.

It may be the first native-born case of mad cow disease. Johanns said there is no evidence the animal was imported. The only other U.S. case, confirmed in December 2003 in Washington state, was in a dairy cow that had been imported from Canada, where three other cases have been found.

Like the 2003 case, the November cow was born before the 1997 feed ban, Johanns said.

The 2003 case prompted nearly 50 countries to impose bans on American beef, causing billions of dollars in losses for the U.S. industry.

Hours after officials confirmed the new case, Taiwan reimposed its ban. Japanese officials said they would seek more information about the new case.

Ed Loyd, an Agriculture Department spokesman, said Saturday that officials were talking with Taiwan authorities “to assure them of the safety of U.S. beef and that our interlocking safeguards did work as they should have to protect human and animal health.”

He added, “We are hopeful that this will only be a temporary ban on U.S. beef.”Mad cow disease is the common name for bovine spongiform encephalopathy, or BSE. A form of the brain-wasting disease in people, variant Creutzfeldt-Jakob disease, is fatal and has been linked to the consumption of contaminated meat. The disease has killed about 150 people worldwide, mostly in Britain, where there was an outbreak in the 1990s.