Anaheim, Calif. ? Ervin Santana had no idea the Boston Red Sox were by far the most potent offensive team in the major leagues.

Perhaps that was a good thing.

“No matter for me who’s hitting, who’s pitching,” the 22-year-old right-hander said after facing the Red Sox for the first time.

The rookie took a two-hit shutout into the eighth inning, and the Los Angeles Angels beat Boston, 4-2, Saturday in a matchup of AL division leaders.

“Ignorance is bliss,” Angels manager Mike Scioscia said. “Whether he’s facing Boston or a team that’s not as talented offensively, you’ve still got to make pitches.”

And that Santana did, limiting the Red Sox to two baserunners before fading in the eighth. By that time, the Angels had provided him with enough offense for their sixth victory in nine games.

“He got ahead of a lot of hitters, and his command was amazing,” catcher Jose Molina said. “It’s hard to hit a guy whose command was so good. He had to have his best stuff today.”

Los Angeles pitcher Ervin Santana delivers against Boston. Santana took a shutout into the eighth inning, and the Angels defeated the Red Sox, 4-2, Saturday in Anaheim, Calif.

The Red Sox entered with a big-league-leading .285 team batting average, 689 runs and 493 walks.

Santana (7-5), who had an 11.34 earned-run average in four previous daytime starts, allowed five hits and two runs in 72â3 innings while throwing 111 pitches. He walked none and struck out five – all in the first two innings – while winning for the fourth time in five decisions since the All-Star break.

“He threw with velocity, movement, four different pitches, all for strikes,” Red Sox manager Terry Francona said. “Even the balls that ended up over the middle of the plate all had movement. And early on, there weren’t too many over the middle of the plate.”

Santana retired his first 11 batters and 21 of the first 23. The only baserunners for the Red Sox in the first seven innings were David Ortiz, who hit a two-out double in the fourth, and Edgar Renteria, who doubled to start the seventh.

Kevin Millar and Bill Mueller singled to open the eighth. Santana retired the next two batters before Johnny Damon singled to load the bases. Scot Shields relieved and allowed a two-run single to Renteria before striking out Ortiz on an off-speed pitch to end the inning.

“I was able to hit a pretty good spot with it; he swung over the top of it,” Shields said. “That pitch wasn’t even in my mind, and Jose (Molina) called for it. I give him credit for putting down those fingers.”

Tigers 3, Blue Jays 2, 13 innings

Detroit – Magglio Ordonez doubled in the winning run with one out in the 13th inning, leading Detroit past Toronto. Placido Polanco singled off Miguel Batista (5-4) to open the inning, then moved to second when Chris Shelton walked. Ordonez’s hit sailed over left fielder Reed Johnson to the wall.

Franklyn German (4-0) worked the last 11â3 innings for the Tigers, who have won six of seven.

Tigers starter Jason Johnson gave up two runs – one earned – and four hits in eight innings.

Indians 6, Orioles 1

Cleveland – Cliff Lee remained unbeaten since July 8, pitching seven strong innings as Cleveland defeated Baltimore. Lee (13-4) allowed one run and four hits, but only two after the first inning. The left-hander hasn’t lost in his last seven starts, going 4-0.

Travis Hafner and Victor Martinez each hit a two-run homer off Rodrigo Lopez (12-7) for the Indians. Cleveland (67-56), which is 11 games over .500 for the second time, is 81â2 games behind AL Central-leading Chicago – the closest the Indians have been since June 19.

Mariners 8, Twins 3, 10 innings

Minneapolis – Richie Sexson hit a grand slam in the 10th inning, and Seattle snapped Minnesota’s six-game winning streak. Seattle rookie Felix Hernandez allowed five hits and struck out nine in eight innings. He shook off a shaky first inning and dominated the final seven, mixing a 95-mph fastball with an 82-mph changeup and a devastating curveball.

Jamal Strong led off the 10th with a pinch-hit triple off Matt Guerrier (0-2) and scored on Yuniesky Betancourt’s single to give the Mariners the lead.

Devil Rays 4, Rangers 2

St. Petersburg, Fla. – Jorge Cantu homered and tied a career high with four RBIs, and Scott Kazmir allowed one run in six innings as Tampa Bay beat Texas.

Cantu hit a two-run homer in the fourth and drove in two more runs with a single one inning later. He has a team-best 19 homers and 81 RBIs.

Kazmir (7-8) equaled a career best with 10 strikeouts. The 21-year-old left-hander allowed four hits and two walks.

Yankees 5, White Sox 0

Chicago – Shawn Chacon throttled Chicago’s punchless offense, and Alex Rodriguez hit a two-run double as New York blanked the White Sox, sending them to a season-high seventh straight loss.

Chacon (2-1) allowed four hits in eight sharp innings for his second straight victory, and the Yankees again beat former teammate Orlando Hernandez.

El Duque was warned for throwing a pitch behind Rodriguez, committed his first two errors in 109 games and also was called for a balk. He gave up six hits and five runs – four earned – in six-plus innings.