KNOXVILLE, TENN. ? Brandon Hoyte’s tackle might have changed the course of the season for Notre Dame. It certainly altered ninth-ranked Tennessee’s outlook Saturday.

Tennessee lost the second member of its heralded freshman quarterback duo, and the Fighting Irish capitalized with an interception return for a touchdown in a 17-13 victory.

Erik Ainge separated his right shoulder on the final play of the first half when he recovered his own fumble and was tackled by Hoyte for a 14-yard loss. Ainge didn’t return.

“You don’t just hit people to tackle them. You tackle them so they won’t get back up. I say that respectfully,” Hoyte said.

Ainge’s injury came a week after Brent Schaeffer broke his collarbone. Junior Rick Clausen, the brother of former Tennessee quarterback Casey Clausen, replaced Ainge in the second half and almost immediately made a big mistake.

Clausen was being sacked by Derek Landri when he let the ball go. Notre Dame’s Mike Goolsby caught it and returned it 26 yards for a touchdown and a 14-10 lead. The Irish (6-3) never trailed again.

The Vols (7-2) have a week off to regroup. Coach Phillip Fulmer said he didn’t know when Ainge would return.

No. 4 Cal 28, Oregon 27

Berkley, Calif. — Geoff McArthur caught eight passes for 121 yards and two touchdowns for Cal. Aaron Rodgers passed for 275 yards and three TDs, and J.J. Arrington ran for 188 yards and a score for Cal (7-1, 5-1 Pac-10). Kellen Clemens threw four TD passes in the first half for Oregon (5-4, 4-2).

No. 5 Wisconsin 38, Minnesota 14

Madison, Wis. — Wisconsin’s Anthony Davis ran for 124 yards and two touchdowns, and quarterback John Stocco threw for a career-high 297 yards and a touchdown. Stocco also ran for two TDs as the Badgers moved into a first-place tie with Michigan atop the Big Ten at 6-0. The Gophers (6-4, 3-4) lost for the fourth time in five games.

No. 8 Georgia 62, Kentucky 17

Lexington, Ky. — Georgia’s David Greene passed for 259 yards and set an NCAA Division I-A record for most wins by a quarterback with 40. Georgia (8-1, 6-1 SEC) scored on six consecutive possessions against the Wildcats (1-8, 0-6).

Thomas Brown rushed for 130 yards and had three touchdown runs for Georgia, which won its fourth straight.

Clemson 24,

No. 11 Miami 17, OT

Miami — Reggie Merriweather ran for a career-high 114 yards and three TDs, including a two-yard score in overtime for Clemson (5-4, 4-3 ACC).

On its overtime possession, Miami moved to the Clemson five, but three straight incompletions by Brock Berlin sealed the Hurricanes’ second straight loss. The loss knocked the Hurricanes (6-2, 3-2) out of first place.

No. 12 Virginia 16, Maryland 0

Charlottesville, Va. — Wali Lundy ran for two touchdowns, and Virginia (7-1, 4-1 ACC) remained in a first-place tie. Alvin Pearman led the Cavs with 170 yards, and Lundy added 107 yards.

No. 13 Florida State 29, Duke 7

Tallahassee, Fla. — Wyatt Sexton bailed out Chris Rix in the second half and completed 11 of 15 passes for 220 yards as the Seminoles scored 20 unanswered points. Florida State (7-2, 5-2 ACC) intercepted three passes and forced two fumbles.

No. 15 West Virginia 42, Temple 21

Morgantown, W.Va. — Kay-Jay Harris caught two touchdown passes and ran for two more to lead West Virginia (8-1, 4-0 Big East).

No. 18 Virginia Tech 27, North Carolina 24

Chapel Hill, N.C. — Mike Imoh ran for 236 yards and two touchdowns as Virginia Tech defeated North Carolina, which missed a 54-yard field goal with a minute left. The Hokies (7-2, 4-1 ACC) have won five straight games.

No. 20 Iowa 23,

Purdue 21

Iowa City, Iowa — Drew Tate threw two touchdown passes, and Iowa (7-2, 5-1 Big Ten) forced five turnovers and blocked two field goals. Brandon Kirsch threw three touchdown passes for Purdue, but he lost a fumble and threw two interceptions in the fourth quarter.

Cincinnati 52,

No. 21 Southern Miss 24

Hattiesburg, Miss. — Gino Guidugli threw three of his school-record five touchdown passes to Hannibal Thomas to lead Cincinnati. Guidugli passed for 308 yards for Cincinnati (5-4, 4-2 Conference USA), which snapped the Golden Eagles’ 13-game league winning streak and beat a ranked team for the first time in four years.

No. 23 ASU 34, Stanford 31

Tempe, Ariz. — Andrew Walter threw his fourth TD pass with nine seconds left for Arizona. Walter was 28-for-43 for 415 yards and broke John Elway’s Pac-10 record for touchdown passes with 80.

No. 24 Boston College 21, Rutgers 10

Boston — Paul Peterson scored on a one-yard run and threw for a TD to lead Boston College (6-2, 2-1 Big East).