Seattle ? The Stanford Cardinal never got a chance to pull off another last-second victory.

The top-ranked Cardinal lost for the first time this season Saturday, falling 75-62 to Washington two days after rallying to beat Washington State on a buzzer-beater.

“Nobody likes to lose, especially when you have 26 wins straight,” center Rob Little said. “We can’t always have a miraculous comeback.”

Washington’s quick and athletic defense forced Stanford into 18 turnovers, and the Cardinal (26-1, 17-1 Pac-10) shot only 39 percent from the field. Starters Josh Childress and Matt Lottich were in foul trouble early, and Lottich scored just two points on 1-of-11 shooting from the field.

“We were one game away from something pretty special, and we didn’t get it done,” coach Mike Montgomery said. “It will take a while to get over that.”

The Cardinal, who also beat Arizona last month on a last-second shot, had a tough trip to the state of Washington. On Thursday night, it took Lottich’s desperation three-pointer to beat eighth-place Washington State 63-61.

“Now we need to go undefeated,” Little said, looking ahead to the conference and NCAA tournaments.

The Cardinal’s loss left No. 2 Saint Joseph’s (27-0) as the only undefeated team in the country.

Tre Simmons scored 16 points for unranked Washington (17-10, 12-6), enjoying its first winning season since 1999.

Chris Hernandez led Stanford with 21 points.

No. 5 Miss. State 82, Alabama 81, OT

Washington's Tre Simmons lifts teammate Will Conroy (5) after the Huskies beat No. 1 Stanford. The Cardinal endured their first loss of the season, 75-62, Saturday in Seattle.

Tuscaloosa, Ala. — Timmy Bowers hit a layup in traffic with a second left in overtime to complete a big rally and lift Mississippi State (25-2, 14-2 Southeastern Conference). Earnest Shelton had 25 points, nine rebounds, four assists and four steals for Alabama, which had an 18-point lead early in the second half.

No. 6 Pittsburgh 59, Villanova 45

Pittsburgh — Chevon Troutman had 17 points and Carl Krauser added 11 for the Panthers (27-3, 13-3 Big East). Allen Ray scored 24 points for Villanova (14-15, 6-10).

No. 16 N.C. State 81,

No. 11 Wake Forest 70

Winston-Salem, N.C. — Engin Atsur made a career-high five three-pointers, helping N.C. State (19-8, 11-5) lock up second place in the Atlantic Coast Conference. Atsur went 5-for-7 from three-point range and scored 17 points. Justin Gray led Wake Forest (19-8, 9-7) with 23 points and Eric Williams added 18.

Boston College 63,

No. 12 Providence 54

Providence, R.I. — Jared Dudley had 15 points and eight rebounds and Boston College (21-8, 10-6 Big East) held Providence (20-7, 11-5) to a season-low 15 first-half points. Ryan Gomes missed his first seven shots and finished with 13 points for Providence.

No. 13 Cincinnati 83, No. 20 Memphis 79

Cincinnati — Tony Bobbitt hit a three-pointer with 36 seconds left, then made two free throws to help Cincinnati (21-6, 12-4) forge a four-way tie for the C-USA championship.

No. 15 So. Illinois 93, Evansville 67

St. Louis — Darren Brooks gave Southern Illinois (25-3) a fast start with eight points in the first 31/2 minutes and finished with 18 points in the Missouri Valley quarterfinal.

No. 17 Wisconsin 70, Indiana 52

Bloomington, Ind. — Devin Harris got Wisconsin started with 16 points in the first 13 minutes, and then the Badgers (21-6, 12-4 Big Ten) relied on a stifling defense. A.J. Moye had 11 points for the Hoosiers (13-14, 7-9).

No. 19 Georgia Tech 63, Florida State 60

Atlanta — Marvin Lewis scored 16 of his 21 points in the second half for Georgia Tech (22-8, 9-7 ACC).

Marquette 81,

No. 25 Louisville 80

Milwaukee — Freshman Dameon Mason’s three-point play with eight-tenths of a second left lifted Marquette (17-10, 8-8 C-USA).