Los Angeles ? Like many Sri Lankans who live abroad, Dr. Anton Ambrose and his wife, Beulah, traveled to their homeland during the holiday season for rest and relaxation.

This year’s trip was to be special because they also were visiting their 33-year-old daughter, Orlantha, who had taken a two-year leave from her job in Los Angeles to teach music to underprivileged kids in her father’s hometown.

But the vacation took a terrible turn Sunday when a tsunami rushed through the coastal areas of Sri Lanka, killing Beulah and Orlantha Ambrose. It wasn’t known whether Anton Ambrose suffered any injuries, friends and family said.

At least 12 U.S. citizens died Sunday in massive tsunamis caused by a 9.0-magnitude quake off the Indonesian island of Sumatra, Secretary of State Colin Powell said. Hundreds more remained missing in 10 countries in southern Asia and Africa.

An Ohio couple, also native Sri Lankans vacationing in their homeland, were also killed when the tsunami hit the coastal town they were visiting, their son said.

As rescue and relief workers in Southeast Asia count the bodies in one of the world’s deadliest disasters, friends of the Ambrose family prayed for the wife and daughter of a respected and beloved doctor.

“A lot of people have lost loved ones in this disaster,” family friend Naj Nagendran, 57, of Thousand Oaks said Monday. “It’s difficult to accept someone is gone.”

From their hometown of Upper Arlington, Ohio, a Columbus suburb, Muttaiya Sundaralingam and his wife, Indirani, left several weeks ago to vacation in Sri Lanka with their daughter, son-in-law and grandchildren.

The younger couple and their children weren’t injured because they were visiting Colombo, on the western coast of the island nation, when the giant waves hit the eastern coast, said Ranjan Manoranjan, president of central Ohio’s Sri Lankan Tamil Assn.

A respected scientist and scholar who retired from Ohio State in 2001, Muttaiya Sundaralingam, 73, was known for his work in determining the structure of nucleic acids and proteins, an area called X-ray crystallography.

Indirani Sundaralingam, 63, was “a great mom, wife and grandmother,” said her son, Mohan Sundaralingam, of Upper Arlington.

A Chicago woman was also among the dead. The body of Tamara Mendis, 55, was recovered in western Sri Lanka, where she had been traveling by train with her daughter when a 30-foot wave crashed over the tracks. Mendis’ daughter survived but could not pull her mother to safety, family members said.

Some American survivors narrowed escaped the deadly waves.

Dipak Jain, dean at Northwestern University’s business school, saw the wall of water barreling toward his hotel on the island of Phuket. The massive wave hit a large lagoon just in front of the building, missing it.

“When the wave started pouring into the lagoon, it reminded me of Niagara Falls,” Jain said Monday by telephone from outside Bangkok. He was visiting Thailand to teach at one of Northwestern’s partner schools.

“We are very fortunate,” Jain said. “When you see things like that, you get a very different perspective on life; you see how short life can be.”