DETROIT ? The Minnesota Twins have played enough games at Comerica Park to know just how tough it is to hit home runs there.

So even they were surprised when they set a stadium record with six homers, including two by light-hitting catcher Henry Blanco, while handing the Detroit Tigers their first loss of the season, 10-5 Saturday.

“The ball was really jumping out there today,” Twins manager Ron Gardenhire said. “They’ve made some adjustments to this park, and the ball carries better than it used to, but days like this are still pretty unusual. Those weren’t cheapies we were hitting, either.”

Luis Rivas, Corey Koskie, Jose Offerman and Lew Ford also connected for the Twins, giving starter Brad Radke plenty of support.

“I don’t know what was going on out there,” said Ford, called up from the minors Friday to replace injured center fielder Torii Hunter. “My head is still kind of spinning, but that was fun.”

The Tigers, who opened last season 0-9 and lost an AL-record 119 games, had been the last unbeaten team in the majors at 4-0.

Blanco, who entered 2004 with a .219 career batting average and 27 homers in six major-league seasons, homered in the second and ninth for his first two hits of the year.

The Tigers were missing manager Alan Trammell, who was serving a one-game suspension for beanballs during a spring-training game against Philadelphia on March 29. Bench coach Kirk Gibson ran the team in his place.

Radke (1-0) improved his career record against Detroit to 16-4, allowing five runs on nine hits and a walk in five innings. He struck out six. Five Twins relievers combined for four scoreless innings to finish it.

Jason Johnson (1-1) lost to the Twins for the first time in six career decisions, lasting just 21/3 innings. He gave up six runs on seven hits, including three homers.

“You can’t be undefeated against a team forever,” he said.

White Sox 7, Yankees 3

New York — Mark Buehrle shut down New York on three singles over eight innings, and Magglio Ordonez and Jose Valentin homered to lead Chicago.

New York’s All-Star-laden lineup has scored just 16 runs in five games since its season-opening Tokyo trip, going 2-3 against Tampa Bay and the White Sox. Making his first career start at Yankee Stadium, Buehrle (1-0) allowed only a pair of unearned runs.

Athletics 2, Mariners 1

Oakland, Calif. — Tim Hudson pitched a four-hitter for the first complete game in the majors this season, and Oakland sent Seattle to its fifth straight loss.

Hudson (1-0) threw only 86 pitches and retired his final 11 batters. He struck out two and walked none in his 14th career complete game.

Orioles 11, Devil Rays 3

St. Petersburg, Fla. — Melvin Mora and Larry Bigbie each homered and drove in three runs, leading Baltimore over Tampa Bay.

Javy Lopez and Mora had four hits apiece. Mora hit a two-run homer in the fifth and an RBI single during a four-run sixth. Bigbie had a two-run single in the sixth and an eighth-inning solo homer.

Rafael Palmeiro and Lopez each had two RBIs for the Orioles. Rick Bauer (1-0) gave up a hit in five scoreless innings.

Tampa Bay’s Eduardo Perez hit a two-run homer. Jeremi Gonzalez (0-2) gave up six runs and nine hits in five-plus innings.

Red Sox 4, Blue Jays 1

Boston — Pedro Martinez held Toronto to four hits over 72/3 innings to outpitch Roy Halladay, and Boston scored all its runs on homers.

David Ortiz, Manny Ramirez and Mark Bellhorn connected for Boston, which bounced back from a 10-5 loss to the Blue Jays in its home opener Friday.

Martinez (1-1), who pitched pretty well on opening day but took the loss, struck out seven and walked two. He did not allow a runner past second base until Orlando Hudson homered in the seventh.

Rangers 12, Angels 6

Arlington, Texas — Kenny Rogers won in his return to Texas, and the Rangers hit three home runs in a win over Anaheim.

Mark Teixeira, Michael Young and Hank Blalock, the 20-something infielders the Rangers hope to build around, all homered in Texas’ third straight win. Brad Fullmer had an RBI double and two RBI singles.

Texas has won three straight after losing its first two.