Manhattan ? Notre Dame did it again — another shocker on another opponent’s home court in the NCAA Tournament.

Credit a defense called “The Storm.”

The 11th-seeded Irish received 17 points from Le’Tania Severe and used an active matchup zone to beat No. 3 seed Kansas State, 59-53, Tuesday night in the second round of the East Regional.

Notre Dame (21-10) shut down a team that had been averaging 75 points a game and advanced to the round of 16 for the fifth time in seven years.

“Regardless of what (defense) we were in, we knew we just had to get out on the shooters and make sure we didn’t give them any easy shots,” Severe said. “I didn’t realize we confused them, but I thought we did a great job on defense. We did what we practiced and it worked out for us.”

Notre Dame had not used that particular defense since early January and brought it out at just the right time. Even with its potent offense, Kansas State (29-5) couldn’t recover after going 12:44 without a field goal and had a 22-game home winning streak broken.

“It was a good change of pace for us,” Notre Dame coach Muffet McGraw said. “It enabled us to get out a little better on their shooters and also be able to double-team inside. We call it ‘The Storm’ because we put a lot of pressure on the ball and try to be real aggressive in it.”

The Irish were too aggressive for Kansas State, which shot 33 percent and was 9-for-30 from three-point range.

“I thought for whatever reason that mentally we really froze,” Kansas State coach Deb Patterson said. “We were our own worst enemies a lot of possessions in the second half. I haven’t seen this team play like this all year. It snuck up and got us.”

Kansas State's Nicole Ohlde, center, is trapped by Notre Dame's Courtney LaVere, left, and Jacqueline Batteast. Kansas State lost the East Regional game, 59-53, Tuesday night in Manhattan.

Notre Dame took advantage of the Wildcats’ struggles to open a 45-38 lead on freshman Megan Duffy’s three-pointer with 7:45 left, just enough of a cushion to hold on down the stretch.

Duffy, who had been 5-for-30 from behind the arc coming in, had put Notre Dame ahead to stay at 35-32 with a three-pointer and made four of her team’s eight free throws in the final 1:01. Her reward will be a trip to her hometown of Dayton, Ohio, for a regional semifinal game with Purdue next Sunday.

Another freshman, Courtney LaVere, made two other free throws at the end.

“I was so pleased with the poise of our freshmen to step up and hit free throws like that,” McGraw said.

Kansas State, cheered on by a purple-clad crowd of 11,534, managed a late run, but Notre Dame kept making free throws every time the Wildcats crept to within two points.

Nicole Ohlde’s layup with 28.2 seconds remaining left K-State trailing 55-53, but Duffy made two free throws to take the lead back to four.