Chicago ? Kerry Wood wanted to give the Cubs’ bullpen some rest. Instead, St. Louis hitters gave Wood some extra time off.

Jim Edmonds and Albert Pujols hit consecutive homers in the first inning, and Tino Martinez tied a season high with four RBIs as the Cardinals the Chicago Cubs, 11-8, Friday.

Moises Alou hit three homers and tied a career best with five RBIs, but the Cubs lost for the eighth time in 10 games. It was the first three-homer game of his career.

Sammy Sosa hit his 511th career homer, tying Mel Ott for 16th place on the career list.

Wood (8-6), who had won his previous three decisions, gave up seven runs, six hits and six walks, tying a season-high. He lasted three-plus innings, his shortest outing since April 9, 2001, at Montreal, when he also pitched three innings.

“It’s obviously disappointing,” he said. “We needed to win today, I knew that coming in. I let our team down, and I really just hurt our bullpen for the rest of the series.”

St. Louis took a two-game lead over Chicago in the NL Central as the Cubs used five relievers. Brett Tomko (5-5) gave up three runs and seven hits in six innings, struck out five and walked one.

Wood gave up the homers to Edmonds and Pujols in the first, Edmonds’ 26th and Pujols’ 25th.

St. Louis made it 5-0 in the second following a leadoff walk by Edgar Renteria on Tomko’s run-scoring single, Bo Hart’s RBI double and Edmonds’ sacrifice fly.

“I guarantee that there was no one in that lineup today excited about taking their swings,” Cardinals manager Tony La Russa said. “This guy (Wood), the league is hitting .200 against him, and he is so tough. His location was off a little bit and the ball was carrying, so we took the advantage.”

Rockies 8, Brewers 6

Milwaukee — Jay Payton and Juan Uribe drew bases-loaded walks from Leo Estrella in the eighth inning as Colorado rallied. With the bases loaded and one out, left fielder Geoff Jenkins made a spectacular diving catch near the line to rob Larry Walker of a hit. But Estrella (2-1) then walked Payton and Uribe. Steve Reed (5-1) threw 1 1/3 innings of scoreless relief, and Justin Speier pitched the ninth for his third save in five chances.

Marlins 2, Phillies 1

Philadelphia — Derrek Lee hit a go-ahead single off Jose Mesa with two outs in the ninth inning, leading Florida. Mesa (3-5) walked Mike Lowell with two outs in the ninth, and Juan Encarnacion singled Lowell to third. Lee followed with a single up the middle on a 3-2 fastball. Braden Looper (4-2) pitched 1 2/3 innings and won despite allowing the tying run in the eighth.

Mets 7, Reds 2

Cincinnati — Tom Glavine (6-8) pitched seven strong innings for his first victory since May 18, and Jeromy Burnitz hit a long three-run homer. The Mets, who had 14 hits, batted around in the seventh for four runs off Jimmy Haynes (1-8) and two relievers.

Pirates 3, Astros 2

Pittsburgh — Reggie Sanders homered in the eighth for Pittsburgh. Sanders’ one-out shot into the left-field seats came off Pete Munro (3-4) and was his 14th of the season. Brian Boehringer (4-2) got the victory by pitching two innings, despite allowing the tying run in the seventh. The Pirates trailed 1-0 until reliever Brandon Puffer threw a two-base wild pitch that scored Brian Giles from second in the sixth inning. Jack Wilson followed with an RBI single that put the Pirates ahead 2-1.

Braves 8, Expos 6

Atlanta — Andruw Jones homered for the second straight game and Russ Ortiz won his fourth straight start to lead Atlanta. Ortiz (11-4) moved into a tie with Colorado’s Shawn Chacon for the most victories in the NL. He fell behind 4-1, then settled down and retired 10 of his last 12 batters. The Braves closed to 4-3 with two runs in the fourth, then went ahead with four in the sixth, knocking out Tomo Ohka (7-8) in the process.

Diamondbacks 3, Dodgers 1, 10 innings

Los Angeles — Quinton McCracken hit a two-run single in the 10th inning. Tom Martin (0-2) opened the 10th by giving up consecutive singles to Alex Cintron and Luis Gonzalez before Guillermo Mota allowed a single to Shea Hillenbrand. Oscar Villarreal (6-4) pitched the ninth, striking out the side in order.

Giants 8, Padres 6

San Diego — Barry Bonds hit a two-run homer, his 25th, to highlight a five-run fourth inning and J.T. Snow also connected as San Francisco Giants beat San Diego. Jesse Foppert (5-7) allowed five runs and six hits in five innings, struck out six. Jake Peavy (8-6) lasted only four innings, his shortest outing of the year.