Elderly people may be better off without beta-blocker eyedrops.

The question: Do beta-blocker eyedrops, often prescribed for the treatment of glaucoma, have adverse effects on the lungs of the elderly?

Past studies have shown that beta-blocker drops may exacerbate symptoms for those with asthma and other breathing problems.

This study examined whether the eyedrops affect the lungs of elderly people without previously diagnosed breathing problems. The researchers compared 2,645 elderly glaucoma patients who used beta-blocker drops and 9,094 patients of the same age who did not. Those who used the drops were more than twice as likely to develop breathing problems in the first year after using the drugs than those who did not use drops.

Who may be affected by these findings? Glaucoma patients over 65 who do not have lung problems.

Caveats: The results are not based on a randomized trial. Some of the researchers have received funding from companies that make glaucoma drops.

Bottom line: Elderly glaucoma patients, especially those being treated for asthma, may wish to consult their physician about using medications such as miotics instead of beta-blocker eyedrops.

Find this study in the Dec. 14 issue of the British Medical Journal or www.bmj.com.