FDA expands use of cervical cancer vaccine up to age 45

KU doctor says it's great news for a lot of people

photo by: Merck via AP

This undated image provided by Merck on Friday, Oct. 5, 2018 shows a vial and packaging for the Gardasil 9 vaccine. The U.S. Food and Drug Administration expanded the use of the company's cervical cancer vaccine to adults up to age 45.

U.S. regulators have expanded the use of Merck’s cervical cancer vaccine to adults up to age 45.

The vaccine was previously only for preteens and young adults through 26. The Food and Drug Administration on Oct. 5 approved Gardasil 9 for women and men through age 45.

The vaccine protects against the human papilloma virus — or HPV — which can cause cervical cancer, certain other cancers and genital warts. The virus is very common and is spread through sex. In most cases, HPV doesn’t cause any problems, but some infections persist and eventually lead to cancer.

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The Centers for Disease Control and Prevention estimates about 14 million people become newly infected with HPV each year, mostly teens and young adults.

Gardasil was originally approved for girls in 2006 and later for boys — partly to reduce the spread of HPV to girls. Although Gardasil was approved for ages 9 through 26, the shots are especially recommended for boys and girls at 11 or 12, before they first have sex and could get infected. About half of U.S. teens now have had two or three doses.

Company testing done in older adults showed the vaccine also worked for them, too. In women 24 through 45, the original Gardasil was about 90 percent effective three years after the women received a third dose.

Dr. Kevin Ault, a gynecologist at the University of Kansas Health System, said in a news release Friday that this is great news for a lot of people.

The HPV virus causes 43,000 new cancer cases each year, the release said, and of those, “we could prevent 90 percent of them if everyone was vaccinated,” Ault said.

Rates of vaccination have been low in Kansas, however. According to data from the KU Cancer Center, as of August 2014, just 6 percent of Douglas County youths ages 11 to 18 had received all HPV vaccinations; 2016 data from the CDC shows that statewide in Kansas, 45.6 percent of girls and 26 percent of boys had completed the series by their 17th birthdays.

The latest version of Gardasil protects against nine strains of HPV, four more than the original.

According to the CDC, each year about 33,700 women and men are diagnosed with a cancer caused by an HPV infection, including 12,000 women with cervical cancer, which kills about 4,000 annually.

Merck said the list price for Gardasil 9 is $205 per dose. Two doses are needed for those vaccinated before 15, and three are recommended for older people.

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