Chicago ? Brewers manager Ned Yost found out how valuable Brooks Kieschnick is.

Kieschnick led off the 10th inning with a pinch-hit homer and Geoff Jenkins added a three-run home run as the Milwaukee Brewers defeated the Chicago Cubs, 12-6, Wednesday.

Keith Ginter hit the Brewers first pinch-hit home run of the season in the seventh inning.

Kieschnick, used both as a reliever and a pinch-hitter by the Brewers, homered off Cubs reliever Todd Wellemeyer (1-1), who allowed six runs — five earned — in the 10th. It was Kieschnick’s third home run of the season.

“He’s been swinging the bat great and he has been pitching good, too. He’s been a good addition for our ball club,” Yost said.

Kieschnick played outfield for the Cubs in 1996-97.

Two of Kieschnick’s three home runs have come against the Cubs.

“It is nice, but you want home runs against anybody,” Kieschnick said. “As long as we go out there and get a win it doesn’t matter who we are playing.”

The Cubs were without reliever Kyle Farnsworth, who was battling a stomach flu.

Milwaukee's Brooks Kieschnick connects for a 10th-inning home run against the Cubs. The Brewers won, 12-6, Wednesday in Chicago.

“No matter what happened today it just didn’t seem to work,” Cubs manager Dusty Baker said.

Padres 7, Rockies 6

San Diego — Rookie Miguel Ojeda hit his first big league homer and drove in four runs, and Donaldo Mendez hit a go-ahead sacrifice fly as San Diego beat Colorado. The Padres snapped the Rockies’ four-game winning streak and denied what would have been their first road sweep in more than two years.

Dodgers 6, Giants 0

San Francisco — Hideo Nomo allowed two hits over seven dominant innings, and Adrian Beltre hit a three-run homer as Los Angeles defeated San Francisco. Nomo (9-6) won his third straight start in overwhelming fashion, silencing the Giants’ lineup in his 13th career victory over San Francisco — the Japanese right-hander’s personal best against any opponent.

Cardinals 9, Reds 6

St. Louis — Bo Hart, Jim Edmonds and Scott Rolen homered in the first inning, leading Matt Morris and St. Louis past Cincinnati. The Cardinals connected early against Paul Wilson (5-5). He started a few hours after drawing a five-game suspension for his actions in a brawl against the Cubs last week, a penalty that is set to begin today. Ken Griffey Jr. hit his 476th career homer.

Phillies 8, Braves 1

Atlanta — Vicente Padilla pitched four-hit ball over seven innings for his third win over Atlanta this season. Mike Lieberthal drove in three runs for the Phillies, who jumped ahead of Greg Maddux just two pitches into the game after Jimmy Rollins hit an RBI triple.

Mets 6, Marlins 3

New York — Rookie Jose Reyes drove in three runs, and Steve Trachsel pitched seven sharp innings and had a sacrifice fly as New York ended its four-game losing streak. Trachsel (6-5) allowed three runs and eight hits while striking out five. Closer Armando Benitez, who blew a save in the ninth inning of Sunday’s 7-3 loss to the New York Yankees, came in with the bases loaded and none out in the eighth and retired six straight for his 18th save in 23 chances.

Pirates 6, Expos 5

Montreal — Pinch-hitter Kenny Lofton drove in the go-ahead run with a sacrifice fly as Pittsburgh scored three unearned runs in the ninth inning then held on for a win over Montreal. Reggie Sanders and Jeff Reboulet homered for Pittsburgh, which ended a three-game losing streak.

D’backs 3, Astros 2

Phoenix — Lyle Overbay homered and Elmer Dessens earned his first victory since May 25 as Arizona won its eighth game in a row. The Diamondbacks swept consecutive three-game series from the Astros and Cincinnati.