Boston ? The way Trot Nixon has been hitting, even baseball’s best pitchers are vulnerable.

Nixon hit a tiebreaking single off relief ace Brendan Donnelly in the seventh inning, and the Boston Red Sox overcame a five-run deficit to beat the Anaheim Angels, 10-9, Tuesday.

“To get the go-ahead run in the bottom of the seventh, it doesn’t matter if it was against Donnelly or against a young kid. It feels good,” Nixon said.

In his last 33 games, Nixon has 26 RBIs and is batting .378, raising his average from .297 to .322. He’s 3-for-4 in his career against Donnelly.

“This is the year Trot’s established himself as one of the best right fielders in the game,” said Kevin Millar, who hit a three-run homer in Boston’s seven-run third. “He’s been as consistent as can be.”

Donnelly (1-2) had been consistent, allowing just two earned runs in his first 50 innings, a 0.36 ERA. But since then the winning pitcher in this year’s All-Star game has given up three earned runs in 42/3 innings, boosting his ERA to 0.82.

He had retired 37 of the first 45 batters he faced this season but allowed a leadoff walk to Manny Ramirez in the seventh. Ramirez took second on a groundout before Millar stuck out. Then Nixon came to the plate.

Mike Timlin (4-3) got the win. Byung-Hyun Kim got the last three outs for his eighth save in nine chances.

Boston won despite Jeff Suppan’s struggles in his return to the Red Sox. Pitching for them for the first time since Sept. 17, 1997, Suppan, a former Kansas City Royal acquired Thursday from Pittsburgh, allowed seven runs in five innings.

“My focus was there. I just wasn’t able to execute pitchers as well as I would have liked,” he said.

Suppan was 5-0 in his last six starts with Pittsburgh but left Tuesday’s game with the score 7-all after five innings, the most runs he has allowed in any of his 22 starts this year. And he served up three homers after allowing a total of 11 in 141 innings with Pittsburgh.

Newly-acquired Red Sox pitcher Jeff Suppan, a former Kansas City Royal, hurls against Anaheim. Suppan started poorly, but the Red Sox rallied for a 10-9 victory Tuesday in Boston.

Orioles 3, Twins 2

Baltimore — Jason Johnson and four relievers combined on a six-hitter, and Luis Matos drove in two runs as Baltimore defeated Minnesota. Brook Fordyce had two hits and scored twice for the Orioles, who have won 13 of 16 at Camden Yards. Johnson (9-5) allowed two runs and five hits in six-plus innings to improve his lifetime record against the Twins to 5-0. Kenny Rogers (8-6) gave up three runs, two earned, and nine hits in seven innings for Minnesota.

Mariners 2, Indians 1

Cleveland — Jamie Moyer became the AL’s third 15-game winner, leading Seattle past Cleveland. Moyer (15-5) allowed one run and three hits in seven innings to join Oakland’s Mark Mulder and Toronto’s Roy Halladay for the league lead in victories. Ichiro Suzuki had three hits for the AL West-leading Mariners, who have won six of seven. C.C. Sabathia (9-7) got stronger as the game progressed. He gave up nine hits, but only two after the fourth inning, in eight innings.

Devil Rays 5, Blue Jays 4, 10 innings

St. Petersburg, Fla. — Travis Lee homered and singled in the winning run with two outs in the 10th inning, giving Tampa Bay a comeback victory over Toronto. Tom Wilson hit a tiebreaking, two-run double with two outs in the eighth inning to put Toronto ahead 4-2, but the Devil Rays rallied with two outs in the ninth against Cliff Politte. Damian Rolls walked and scored on Marlon Anderson’s single. After Anderson stole second, pinch-hitter Al Martin tied it with a single to right on a 3-2 pitch. Rocco Baldelli reached with one out in the 10th when third baseman Eric Hinske misplayed his grounder for an error. Aubrey Huff drew a walk from Juan Acevedo (1-5) and, after Toby Hall flied out, Lee singled to left to win it.

Athletics 7, Tigers 2

Detroit — Rookie Rich Harden won again, pitching six strong innings for Oakland. Harden (3-0) gave up two runs and five hits in six innings. He struck out six and walked two to give the A’s their ninth win in 12 games. The 21-year-old righty has allowed just four runs over 27 innings with 23 strikeouts in three starts since Oakland purchased his contract from Triple-A Sacramento July 17. Wellington native Nate Cornejo (3-10) gave up six runs on eight hits and two walks over 41/3 innings.

Yankees 6, Rangers 2

New York — Derek Jeter homered in each of the first two innings, and Hideki Matsui and Jason Giambi also hit home runs, leading Roger Clemens and New York over Texas. Jeter hit a leadoff homer in the first and a two-run shot in the second off Colby Lewis (4-7). It was his first multihomer game of the season and fourth of his career. Matsui added a two-run homer in the first and Giambi hit his AL-leading 32nd home run in the fifth. Clemens (11-7) earned his 304th career victory, allowing one run and five hits in seven innings. He struck out four and walked two.