Zika virus ‘spreading explosively’ in Americas, World Health Organization warns

Gleyse Kelly da Silva holds her daughter Maria Giovanna as she sleeps in their house in Recife, Pernambuco state, Brazil, on Wednesday, Jan. 27, 2016. Brazilian officials still say they believe there's a sharp increase in cases of microcephaly and strongly suspect the Zika virus, which first appeared in the country last year, is to blame. The concern is strong enough that the U.S. Centers for Disease Control and Prevention this month warned pregnant women to reconsider visits to areas where Zika is present.

GENEVA — Declaring that the Zika virus is “spreading explosively,” the World Health Organization announced it will hold an emergency meeting of independent experts Monday to decide if the outbreak should be declared an international health emergency.

At a special meeting Thursday in Geneva, WHO Director-General Dr. Margaret Chan said the virus — which has been linked to birth defects and neurological problems — was becoming much more of a threat. One WHO scientist said the Americas could see up to 4 million cases of Zika in the next year.

Chan said although there was no definitive proof that the Zika virus was responsible for a spike in the number of babies being born with abnormally small heads in Brazil, “the level of alarm is extremely high.” She also noted a possible relationship between Zika infections and Guillain-Barre syndrome, which can cause temporary paralysis.

U.S. cases

Health officials say the number of U.S. residents diagnosed with Zika infections in the past year has grown to 31.

All of them are believed to have caught the infection while traveling in the Caribbean or Latin America where there are outbreaks of the tropical illness.

Officials said Thursday the 31 people are in 11 states and Washington. In U.S. territories, Puerto Rico has 19 confirmed cases and the U.S. Virgin Islands has one.

The government is looking at the issue of blood donations from travelers, although officials think the virus is gone from an infected person’s blood in a week or less.

“The possible links, only recently suspected, have rapidly changed the risk profile of Zika from a mild threat to one of alarming proportions. The increased incidence of microcephaly is particularly alarming, as it places a heart-breaking burden on families and communities,” Chan said.

The Zika virus was first detected in 1947 and for decades only caused mild disease, but Chan noted that “the situation today is dramatically different.” According to the U.S. Centers for Disease Control, the Zika virus is now in more than 20 countries, mostly in Central and South America. It is spread by the same mosquito that spreads dengue and yellow fever.

Earlier this month, the CDC said pregnant women should consider postponing trips to more than a dozen countries with Zika and advised women trying to get pregnant or thinking of getting pregnant to speak to their doctor before traveling and to take extra precautions to avoid mosquito bites.

Sylvain Aldighieri, head of WHO’s epidemic response team in the Americas, estimated there could be 3 to 4 million Zika infections in the region over the next year. He said the agency expects “huge numbers” of infections because of the widespread presence of the Aedes mosquitoes that spread Zika and because people in the region have no natural immunity.

WHO also warned China and all other countries that have dengue fever to be on the lookout for Zika infections. The agency said it could be many years before a vaccine is available and it might take six to nine months before there’s any data showing a causal relationship between Zika and the babies born with malformed heads.

Chan cited four main reasons why WHO was “deeply concerned” about Zika: The possible link to birth defects and brain syndromes, the prospect of further spread, a lack of immunity among people living in the newly affected areas and the absence of vaccines, treatments or quick diagnostic tests for the virus.

The U.N. health agency called the special session in part to convey its concern about an illness that has sown fear among many would-be mothers, who have responded by covering themselves head-to-toe in clothing in largely tropical Brazil or putting on many coats of insect repellent.

Declaring a global emergency is akin to an international SOS signal and usually brings more money and action to address an outbreak. The last such emergency was announced for the devastating 2014 Ebola outbreak in West Africa, which eventually ending up killing over 11,000 people. Polio was declared a similar emergency the year before.

Still, convening an emergency committee does not guarantee that a global emergency will be declared — WHO has held 10 such meetings to assess the Middle Eastern respiratory syndrome coronavirus and no emergency has been announced.

One reason why WHO is examining the Zika virus so quickly may be because the agency was criticized for its slow response to Ebola; nearly 1,000 people had died before WHO declared it to be an international emergency. The Associated Press found that senior agency officials resisted the Ebola declaration for two months, citing political and economic reasons.

Marcos Espinal, WHO’s director of infectious diseases in the Americas region, said Brazil is conducting studies to determine if there is scientific evidence that Zika virus causes birth defects and neurological problems.

Brazilian authorities estimate the country could have up to one million Zika infections by now. WHO said given the “intense transmission” of Zika there, the number of new infections in Brazil next year would probably fall.

Brazil’s Zika outbreak and its spike in microcephaly cases among babies have been concentrated in the poor and underdeveloped northeast, but the prosperous southeast, where Sao Paulo and Rio de Janeiro are located, is the nation’s second hardest-hit region. Rio de Janeiro is of special concern, since it will host the Aug. 5-21 Summer Olympic games that are expected to be attended by millions from around the world.

Earlier this week, officials in Rio ramped up their fight against the mosquitoes that spread Zika, dispatching fumigators to the Sambadrome, where the city’s Carnival parades will take place next month.

There is no specific treatment or vaccine for Zika, which is related to dengue. Scientists have struggled for years to develop a dengue vaccine; the first such shot made by Sanofi Pasteur was licensed last year in Brazil.

Despite the concern shown at WHO, a leading U.S. health official said Thursday that he doubts the United States is vulnerable to a widespread outbreak of the Zika virus. Dr. Anthony Fauci said hopefully the Zika virus can be kept at bay with “mosquito vector control.”

This 2006 photo provided by the Centers for Disease Control and Prevention shows a female Aedes aegypti mosquito in the process of acquiring a blood meal from a human host.

Five things to know about Aedes mosquitoes

Behind the tropical disease outbreaks that have exploded in Latin America is a tiny menace that just won’t go away.

It’s called the Aedes aegypti, a species of mosquito that has played a villainous role in public health history and defeated attempts to eradicate it from the New World.

Five things to know about the bug:

First in Africa

Aedes aegypti is a small, dark, hot-weather mosquito with white markings and banded legs. Scientists believe the species originated in Africa, but came to the Americas on slave ships. It’s continued to spread through shipping and airplanes. Now it’s found through much of the world, including the southern United States.

Once yellow fever

Early in the 20th century, scientists showed it was the engine behind devastating yellow fever outbreaks. It became known as the yellow fever mosquito, although that name has been used less often since a successful vaccine was developed against yellow fever. Since then, it’s also been identified as a carrier for other tropical illnesses such as dengue fever, chikungunya and Zika fever. Scientists are investigating whether other types of mosquitoes are spreading Zika in Latin America and the Caribbean, too.

City dweller

Aedes aegypti is the primary spreader of Zika and some other tropical diseases, largely because of its unusually cozy relationship with people. While other species thrive in more rural areas, or at least in parks and gardens, this is a domesticated species — sort of a housecat mosquito — accustomed to living in apartment buildings and city centers. It prefers biting people to animals and likes to feed indoors, during daylight hours. Also, it is a hardy bug that can be particularly challenging to get rid of.

Killed off, it came back

In the early 20th century, many countries developed programs to destroy all Aedes aegypti mosquitoes through spraying chemicals and other measures. By 1970, it was eradicated from much of South America — including Brazil. But many mosquito-control programs were cut back. Reasons included budget cuts, and concerns about the use of some insecticides, and the yellow fever vaccine made the mosquito’s elimination less critical.

The species roared back. It played a key role in the reemergence of dengue fever in Latin America and the Caribbean, and the recent spread of chikungunya and Zika virus.

Going for blood

Female mosquitoes drink human blood for nutrients used in making eggs. After a female bites an infected person, it can spread the virus through its saliva to its next human victim. Some scientists think Zika may have arrived in Brazil in 2014, carried by visitors attending World Cup soccer games. Perhaps one or more infected visitors were bitten by mosquitoes and started the chain reaction, said Jeffrey Powell, a Yale University mosquito expert who works in Brazil.