London ? The News Corp. phone-hacking scandal claimed two high-ranking executives running the company’s U.S. and British operations as Chief Executive Rupert Murdoch tried to stem the fallout from a growing crisis he had been downplaying.

The resignations of longtime Murdoch intimates Les Hinton as chief executive of Dow Jones & Co. and publisher of its Wall Street Journal and Rebekah Brooks as chief of News International in London came hours apart Friday.

Hinton was in charge of News International and Brooks was editor of its News of the World when many of the hacking incidents are alleged to have occurred. Murdoch closed the 168-year-old tabloid last week amid the scandal.

Murdoch himself apologized Friday to the family of a 13-year-old homicide victim whose phone allegedly had been hacked by News of the World operatives in 2002 while the girl was still missing. A full-page apology he signed was scheduled to appear today in all British national newspapers under a banner headline saying, “We are sorry.”

Members of Parliament had been demanding Brooks’ ouster, but it was Hinton’s exit that was most dramatic, given his 52-year association with Murdoch.

“That this passage has come to an unexpected end, professionally, not personally, is a matter of much sadness to me,” Murdoch said in a statement.

The flight of top executives underscores the severity of the crisis that has News Corp. on the ropes. The company has tried to contain the damage by mounting a public relations offensive after being battered for nearly two weeks by rival news organizations and government officials on both sides of the Atlantic.

On Thursday, it was disclosed that the FBI had launched an inquiry to determine whether Murdoch’s minions hacked into the phones of victims and families of the Sept. 11, 2001, terrorist attacks at the World Trade Center and Pentagon.

Industry experts believe that Friday’s developments are designed to protect Murdoch and his son and heir apparent, James, from further scrutiny by isolating the problem to Brooks and Hinton. The company has hired public relations company Edelman to help navigate the crisis.

“Heads had to roll, and it seems the appropriate heads did roll,” said Laura Martin, media analyst with Needham & Co. “Even the prime minister of Britain, David Cameron, had been saying that Brooks had to go. Maybe Hinton was the sacrificial lamb. They needed someone other than James, so it had to be a pretty senior executive.”

“Murdoch is trying to keep his empire in the U.K. intact,” Martin said.

Robert Eckerstrom, director of Moody’s Capital Markets Research, warned about investing in the company, writing in a note: “The ramifications of the recent discoveries may grow as more questionable practices are uncovered.”

In a statement Friday, Hinton appeared to provide a defense for the Murdochs.

“There had never been any evidence delivered to me that suggested the conduct had spread beyond one journalist,” reiterating what he had testified in Parliament four years ago.