The NFL Draft always is a guessing game. Never has it been accompanied by so much uncertainty.

Not just who will go first overall — the betting favorite is Heisman Trophy winner Cam Newton — but who goes where and when beyond that. Will the Patriots trade down again and again, as they always seem to do? Or will the Jets trade up, as they normally do?

This year, the selection process has the added element of players being locked out by owners, and a judge temporarily blocking the lockout earlier this week. Should the league be forced to reopen for business before or during the draft, the result could be even more chaos.

“The world doesn’t stop spinning, we have to keep running and working,” Baylor guard Danny Watkins said Wednesday. “It’s just disappointing the timing of it, but there’s nothing we can do about it.”

Nothing except prepare for tonight’s opening round of the three-day extravaganza that has been the league’s only order of business since the lockout began March 12.

A record 25 players accepted invitations to attend the draft itself, and 13 were on hand Wednesday for an NFL event with youngsters.

A dozen of them spoke to the media afterward. After the young campers were done, Newton skipped out. The Auburn quarterback took a few minutes to high-five some kids and sign autographs before slipping out a side entrance with a few associates and into a waiting SUV.

The other players expressed little concern the labor impasse would affect the 2011 season.

“This is America’s game,” LSU cornerback Patrick Peterson said. “I can’t see the world without NFL football.”

While matters are worked out in Judge Susan Richard Nelson’s court in Minnesota, the draft is the only game in town. There were concerns that pressure from the locked-out players would persuade many likely high-round draftees to skip the trip to New York.