St. Petersburg, Fla. ? Johan Santana made it look easy.

The AL Cy Young Award winner rebounded from his first loss in a nearly a year, scattering six hits for his second career complete game to lead the Minnesota Twins over the Tampa Bay Devil Rays, 7-1, Friday night.

“He can shut a lot of teams down,” Twins manager Ron Gardenhire said. “He always gives you a chance to win, and he didn’t give them much chance to really get into the game. That’s what a good starter does.”

Joe Mauer went 4-for-5 with a three-run homer, and Justin Morneau added a two-run shot in support of Santana, who won for the 18th time in his last 19 decisions. The Twins have won seven of 10 and halted Tampa Bay’s three-game winning streak.

“They were pretty hot, and they were swinging the bat tonight,” Santana said. “They put the ball in play, and when you do that, you’ve got a chance. That was the case tonight, but we were able to make some plays.”

Santana (5-1) struck out seven and walked none, and the Devil Rays went 0-for-5 with runners in scoring position after Aubrey Huff drove in the only run off the left-hander with a one-out triple in the first.

Angels 4, Tigers 3

Anaheim, Calif. — Kelvim Escobar pitched 71/3 strong innings, Steve Finley tripled in two runs and doubled home another, and Los Angeles beat Detroit to extend its winning streak to five.

Indians 8, Rangers 6

Arlington, Texas — Travis Hafner and Jhonny Peralta hit two-run homers in Cleveland’s seven-run first inning, and the Indians defeated Texas. Cleveland scored all the runs in its highest-scoring inning of the season after two outs.

The homer by Peralta, the No. 9 hitter, was the sixth straight Cleveland hit and chased Pedro Astacio (1-4).

Athletics 6, Yankees 3, 10 innings

New York — Oakland scored three times in the 10th inning without hitting a ball out of the infield, beating Mariano Rivera and New York.

Barry Zito pitched effectively into the eighth, and Oakland got home runs from Eric Byrnes and Bobby Kielty to end a three-game skid. The Yankees have lost four straight and eight of 10.

White Sox 5, Blue Jays 3

Toronto — A.J. Pierzynski hit a go-ahead two-run single in the eighth inning to lead Chicago to its sixth straight victory. Orlando Hernandez (4-1) pitched seven strong innings to help the White Sox improve their major-league-leading record to 22-7. Chicago’s starters are 17-3 with a 2.79 earned-run average.

Red Sox 7, Mariners 2

Boston — Matt Clement won a matchup of unbeaten pitchers, allowing just an unearned run in seven innings while Jamie Moyer faltered, and Bill Mueller drove in four runs to lead Boston over Seattle.

Despite removing Johnny Damon and Edgar Renteria from the lineup because of injuries, the Red Sox won their fourth consecutive game.