Pittsburg ? The Pirates could not wait to see Jose Guillen leave Pittsburgh in 2000. Five years later, they feel much the same way.

In a game featuring mostly long home runs, two by Guillen, the Washington Nationals came back after squandering an early lead to beat the Pirates, 5-4, Wednesday.

Guillen’s second two-homer game in three days came as the teams combined for five homers in the first three innings, helping Pittsburgh take a 4-2 lead Josh Fogg couldn’t hold.

Guillen, a former Pirates player cast off to Tampa Bay in a seemingly minor deal in 2000, went 8-for-14 with four homers, a double and six RBIs as Washington took two of three in the series. He has four multihomer games this season.

Despite driving in 84 runs during a promising rookie season in 1997, Guillen was dealt after the Pirates wearied of his frequent bouts with immaturity and a sometimes casual approach to conditioning. Still, Pittsburgh remains one of Guillen’s favorite stops in the majors.

“I like to come here and play – it’s always going to be a place where I like to come,” Guillen said. “And I got some good pitches to hit.”

Reds 7, Cardinals 6

Cincinnati – Adam Dunn led off two straight innings with home runs, and Cincinnati overpowered slumping Mark Mulder before holding on for a victory over St. Louis.

Dunn moved into a tie for the NL lead with his 19th and 20th home runs to help the Reds.

Washington's Jose Guillen rounds third base and is greeted by coach Dave Huppert after hitting a home run. Guillen had two blasts in the Nationals' 5-4 victory Wednesday in Pittsburgh.

Astros 6, Rockies 2

Houston – Roger Clemens pitched seven strong innings for his 334th win, Morgan Ensberg hit a three-run homer, and Houston completed a three-game sweep of Colorado.

Clemens (6-3) allowed two runs and five hits.

Braves 8, Marlins 0

Atlanta – Andruw Jones hit his NL-leading 21st homer, a two-run shot, and Braves starter Horacio Ramirez (6-4) pitched five shutout innings before leaving because of a strained groin. Jones has hit nine homers in the last 11 games, a streak that began with a two-homer game June 11 against Oakland.

Phillies 8, Mets 4

Philadelphia – Chase Utley had a go-ahead RBI single in a six-run seventh inning, Jim Thome homered, and Kenny Lofton had a three-run double for the Phillies, who won for just the third time in eight games.

Giants 4, D’backs 0

San Francisco – Jason Schmidt pitched eight dominant innings to win consecutive starts for just the second time all season, and the Giants defeated Arizona.

Ray Durham moved back to the leadoff spot and hit an RBI single and scored a run, and Moises Alou had three hits, an RBI and a run as the Giants won for the second time in five games.

Dodgers 6, Padres 4

San Diego – Jayson Werth had a tying homer among his three hits, and Olmedo Saenz had three hits and scored three runs as Los Angeles snapped its season-high eight-game losing streak.

Yhency Brazoban pitched the ninth for his 12th save.

Brewers 9, Cubs 4

Milwaukee – Carlos Lee hit two home runs, including a three-run shot during an eight-run second inning, and Milwaukee beat the Chicago.

Lee added a solo shot in the seventh for his 19th homer. The NL leader with 64 RBIs has two multihomer games this season.

Milwaukee sent 12 men to the plate in the second and knocked out Chicago starter Carlos Zambrano (4-4).