New York ? Jerry Seinfeld and Paul Simon will perform together for one night only to raise money for research into autism.

The concert will be held Sept. 24 at the Kodak Theatre in Los Angeles, hosted by Tom Brokaw of NBC News. It will benefit Autism Speaks, a not-for-profit organization launched earlier this year by NBC Universal boss Bob Wright and his wife, Suzanne.

“I became aware of autism through some friends who are dealing with it and it is heartbreaking,” Seinfeld said in a statement Wednesday. “I wanted to do something to help address this problem and decided to do a show to raise funds for research.”

Tickets will be available beginning Aug. 15. Prices start at $100.