Ames, Iowa Freshman Lyndsey Medders broke out of a long slump with 20 points, and Iowa State knocked off a ranked team for the second time in seven days, beating No. 15 Oklahoma, 69-51, Tuesday.
ISU (9-6, 2-2 Big 12) recovered from a miserable start to drop OU coach Sherri Coale to 0-4 in Hilton Coliseum.
Katie Robinette added 11 points and eight rebounds for Iowa State, which beat then-No. 2 Texas Tech, 64-63, last week. Another shocker seemed improbable after OU (13-3, 3-2) took an 11-1 lead, but Iowa State broke it open with a 25-6 run at the start of the second half.
Medders, who had averaged only 4.9 points in the previous eight games, sparked the run with two three-pointers and a layup and had 15 points in the second half.
OU's leading scorer, Maria Villarroel, scored only seven and committed seven of her team's 23 turnovers.