Seattle ? Washington’s Cody Pickett and Reggie Williams will be on quite the opening stage tonight.

Arguably the nation’s top quarterback-to-receiver combination, Pickett and Williams will play in front of a national TV audience and more than 100,000 frenzied fans when the No. 17 Huskies visit defending national champion Ohio State.

“They’re both big, athletic, very competitive guys,” Washington coach Keith Gilbertson said. “They’re great kids to coach and they like to make plays. The more difficult the challenge, the more they’ve enjoyed the competition.”

Pickett is a senior from Caldwell, Idaho, the son of former Boise State quarterback and pro rodeo roper champion Dee Pickett. Williams is a junior from Lakewood, Wash., a first-team All-American last year.

Their statistics are imposing, and each holds numerous school records.

Last season, Pickett threw for 4,458 yards, the first Pac-10 quarterback to break the 4,000-yard mark in a season.

His school record of 6,873 career yards is way ahead of second-place Brock Huard (5,742) with a full season to go.

Ohio State’s Craig Krenzel agreed the statistics illustrate an excellent quarterback.

“But I didn’t need to hear those numbers to know that he’s an outstanding football player,” Krenzel said. “He’s got a lot of national attention. He does some great things for their offense.”

Pickett has four 400-yard passing games and 12 300-yard games. He has seven of the top 10 single-game totals in school history.

“Cody is a great quarterback. He can do it all,” Williams said. “He’s got a real strong arm, and he can throw it 70 yards if he needs to.”

Pickett doesn’t dwell on his feats. Mention his preseason publicity or the possibility of a Heisman Trophy — it’s called the “H-word” around the Washington program — and it’s clear he’d rather talk about the Huskies.

“It really isn’t a distraction to me,” Pickett said. “I’m focused on our team goals. We felt we underachieved last year as a team. We need to do a lot better this year, and I’m sure we will.”

Williams led the Pac-10 last season and set school records with 1,454 yards receiving and 94 catches. He averaged 111.8 yards a game.

Through his first two seasons, Williams has 149 receptions for 2,427 yards — the best two-year span in Pac-10 history.

Williams said he hasn’t decided whether to skip his senior year and enter the NFL draft after this season, but that decision is expected by many.

In other Top 25 games, it’s North Texas at No. 1 Oklahoma, Central Michigan at No. 4 Michigan, No. 8 USC at No. 6 Auburn, Troy State at No. 7 Kansas State, No. 11 Georgia at Clemson, Fresno State at No. 12 Tennessee, No. 13 Florida State at North Carolina, Louisiana-Monroe at No. 14 LSU, Western Carolina at No. 16 North Carolina State, Duke at No. 18 Virginia, No. 21 Wisconsin at West Virginia, No. 23 Colorado State vs. Colorado (at Denver), and No. 24 Oklahoma State at Nebraska

On Sunday, New Mexico State visits No. 5 Texas and Central Florida is at No. 9 Virginia Tech.