Kansas City, Mo.-based Vanguard Airlines said it would cut about 20 percent of its daily flights and up to 15 percent of its 1,000 jobs.
The reduction of 12 of its 60 daily flights will begin Oct. 4, the airline announced. Notification of the 100 to 150 employees whose jobs are to be cut was under way, spokesman Alan Carr said.
Vanguard's nine executive officers took immediate salary cuts of 25 percent, Carr said.
The announcement came three days after Scott Dickson, chief executive officer of the 7-year-old airline, pleaded with the region's residents and businesses to "fly their hometown airline."
Meanwhile, Eagan, Minn.-based Northwest Airlines said it would shed 10,000 jobs, nearly a fifth of its work force.
"The events of last week will have a lasting impact on all of us," chief executive Richard Anderson said. "Our thoughts and prayers go out to the thousands of innocent victims around the world and their families. We all agree, however, that it is imperative that our industry return to serving the needs of travelers and the global economy."
Northwest already had announced shortly after the attacks that it would reduce its flight schedule. Major carriers American, Continental, Delta and United also have trimmed their schedules by 20 percent since the attacks.