Nomar Garciaparra is doubtful for opening day. Derek Jeter and Kevin Brown might miss out, too.
Garciaparra's injured right wrist is still causing him trouble, and Boston's All-Star shortstop will fly to Virginia on Monday to see a hand specialist.
"Right now, we want to give it more time to heal on its own," Red Sox general manager Dan Duquette said Saturday at Fort Myers, Fla. "To have Nomar with us on opening day is probably doubtful for us."
Duquette said no decision has been made about surgery, which could sideline Garciaparra for several months.
Garciaparra has a split tendon in the wrist, an injury that has lingered since Sept. 25, 1999, when he was hit by a pitch. He played with the problem last season and hit .372 to win his second straight AL batting title.
Garciaparra was shut down when his wrist acted up early in camp.
Jeter, slowed this spring by an assortment of troubles, could start the season on the disabled list. The New York Yankees' shortstop did not take part in drills Saturday because of a right quadriceps injury.
"I can't tell you he'll be ready for the season," manager Joe Torre said before the Yankees played Philadelphia in Clearwater, Fla. "There's no plan. We'll see how he feels. In order not to lose him for an extended period during the start of the season, playing here or playing there makes that difference. You have to be cautious."
Jeter has played in just five games this spring. He has also been sidelined by a right shoulder injury and viral throat infection.
Jeter underwent an MRI on Friday after running for the first time since leaving a game against the Atlanta Braves on March 16.
"We ran a little bit. ... I didn't run 100 percent ... but it was still there," Jeter said after treatment at Legends Field in Tampa. "We decided just to wait."
Brown, who hurt his right Achilles' tendon on Friday, has a sprain. He will miss his last scheduled spring start Wednesday.
"It's stiff," said Brown, who walked with a pronounced limp through Los Angeles clubhouse.
"I'm trying to stay off of it. I'm not going to do anything to really test it. It all depends on how it recovers, how it responds to treatment."
Team physician Dr. Frank Jobe said the worst-case scenario is that Brown may be out a few weeks. He cautioned that there's no way to know for sure until the tendon has been rested and treated.